Recombinant: Superior lot-to-lot consistency, continuous supply, and animal-free manufacturing.
DLX1 (E4T1L) Rabbit mAb (BSA and Azide Free) #57480
Filter:
- WB
- IF
Supporting Data
| REACTIVITY | H M R |
| SENSITIVITY | Endogenous |
| MW (kDa) | 28 |
| Source/Isotype | Rabbit IgG |
Application Key:
- WB-Western Blotting
- IF-Immunofluorescence
Species Cross-Reactivity Key:
- H-Human
- M-Mouse
- R-Rat
Product Information
Product Usage Information
This product is the carrier free version of product #96585. All data were generated using the same antibody clone in the standard formulation which contains BSA and glycerol.
This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.
BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
This formulation is ideal for use with technologies requiring specialized or custom antibody labeling, including fluorophores, metals, lanthanides, and oligonucleotides. It is not recommended for ChIP, ChIP-seq, CUT&RUN or CUT&Tag assays. If you require a carrier free formulation for chromatin profiling, please contact us. Optimal dilutions/concentrations should be determined by the end user.
BSA and Azide Free antibodies are quality control tested by size exclusion chromatography (SEC) to determine antibody integrity.
Formulation
Supplied in 1X PBS (10 mM Na2HPO4, 3 mM KCl, 2 mM KH2PO4, and 140 mM NaCl (pH 7.8)). BSA and Azide Free.
For standard formulation of this product see product #96585
For standard formulation of this product see product #96585
Storage
Store at -20°C. This product will freeze at -20°C so it is recommended to aliquot into single-use vials to avoid multiple freeze/thaw cycles. A slight precipitate may be present and can be dissolved by gently vortexing. This will not interfere with antibody performance.
Specificity / Sensitivity
DLX1 (E4T1L) Rabbit mAb (BSA and Azide Free) recognizes endogenous levels of total DLX1 protein.
Species Reactivity:
Human, Mouse, Rat
Source / Purification
Monoclonal antibody is produced by immunizing animals with a synthetic peptide corresponding to residues surrounding His245 of human DLX1 protein.
Background
Homeobox protein DLX-1 (DLX1) is a member of a family of homeobox genes related to the Drosophila distal-less gene. DLX1 is a transcription factor found in the forebrain of the developing mouse embryo, where it contributes to craniofacial development (1-3). DLX1 also plays a critical role in GABAergic neurogenesis and retinal development (4-7). The DNA-binding activity of DLX1 is mediated by its homeodomain, and DLX1 has been shown to bind to genes that promote neuronal migration and repress neurite growth (8,9). DLX1 expression is regulated by various non-coding RNAs in different cancer types (10-12).
- Stock, D.W. et al. (1996) Proc Natl Acad Sci USA 93, 10858-63.
- Price, M. et al. (1991) Nature 351, 748-51.
- Qiu, M. et al. (1997) Dev Biol 185, 165-84.
- Anderson, S.A. et al. (1997) Science 278, 474-6.
- Bulfone, A. et al. (1998) Neuron 21, 1273-82.
- He, W. et al. (2001) J Neurosci 21, 8854-62.
- de Melo, J. et al. (2005) Development 132, 311-22.
- Le, T.N. et al. (2007) J Biol Chem 282, 19071-81.
- Cobos, I. et al. (2007) Neuron 54, 873-88.
- Wang, J. et al. (2021) BMC Urol 21, 40.
- Li, Q. et al. (2021) Andrologia 53, e14230.
- Kuo, F.C. et al. (2022) Cancer Cell Int 22, 396.
限制使用
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For Research Use Only. Not For Use In Diagnostic Procedures.
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